Progesterone antagonist is:
A. mifepristone
B. regesterone
C. misoprostol
D. prostaglandin
Correct answer: A. mifepristone
Explanation .Progesterone antagonist is: Mifepristone
Explanation
• Mifepristone is a synthetic steroid that blocks progesterone receptors in the uterus.
• It inhibits the action of progesterone, a hormone essential for maintaining pregnancy.
• Used in medical termination of early pregnancy, emergency contraception, and sometimes for Cushing syndrome management.
Other examples
Drug Action
Mifepristone Strong progesterone receptor antagonist
Ulipristal acetate Partial antagonist / selective progesterone receptor modulator
Correct Answer
👉 Mifepristone
Other Options Details :-
Here are the descriptions of all the options:
A. Mifepristone
• Mifepristone is an anti-progesterone drug.
• It blocks the action of progesterone, which is necessary to maintain pregnancy.
• Commonly used as part of medical termination of pregnancy (abortion) in early pregnancy.
It prepares the uterus for expulsion by softening the cervix and making the uterus more sensitive to prostaglandins.
B. Regesterone
• Regesterone is a synthetic progestin (a form of progesterone).
• Used in menstrual disorders such as irregular menstruation, amenorrhea, and dysfunctional uterine bleeding.
• Helps regulate the menstrual cycle and support the luteal phase.
C. Misoprostol
• Misoprostol is a prostaglandin E1 analogue.
• It causes uterine contractions and helps in cervical dilation.
• Used for medical abortion (along with mifepristone), induction of labor, treatment of postpartum hemorrhage, and gastric ulcer prevention.
D. Prostaglandin
• Prostaglandins are naturally occurring hormone-like substances.
• They play an important role in stimulating uterine contractions, cervical ripening, and labor induction.
• Used medically for induced abortion, induction of labor, and postpartum hemorrhage control.
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Writer: Vandita Singh, Lucknow (GS India Nursing Group)