The large amount of progesterone secreted during the secretory phase of the menstrual cycle is response for
A. The onset of ovulation
B. The regulation of menstruation
C. The incidence of capability fragility
D. Sustaining the thick endometrium of the uterus
Correct Answer: D. Sustaining the thick endometrium of the uterus
Explanation :-
During the secretory (luteal) phase of the menstrual cycle, a large amount of progesterone is secreted mainly by the corpus luteum.
This increased level of progesterone is responsible for:
Answer
Sustaining and thickening the endometrium for implantation of a fertilized ovum
Explanation
• Progesterone makes the endometrium more vascular, glandular, and nutrient-rich, preparing it for pregnancy.
• It decreases uterine contractions to help embryo implantation.
• If pregnancy does not occur, progesterone levels fall, leading to menstruation.
Key functions of progesterone in secretory phase
Function Description
Endometrial maturation Converts proliferative endometrium into secretory endometrium
Supports implantation Prepares uterus for fertilized egg
Inhibits uterine motility Prevents expulsion of possible embryo
Maintains pregnancy (if conception occurs) until placenta takes over
Therefore
Large amount of progesterone in secretory phase is responsible for maintaining a thick endometrium suitable for implantation.
Other Options Details
Here is the description of all the options:
A. The onset of ovulation
• This refers to the beginning or triggering of ovulation.
• Ovulation is the release of a mature ovum (egg) from the ovary.
• It occurs around the mid-point of the menstrual cycle, typically due to a surge in luteinizing hormone (LH).
• Signs can include Mittelschmerz (mid-cycle pain), increased basal body temperature, and stretchy cervical mucus.
B. The regulation of menstruation
• This refers to the control and coordination of the menstrual cycle.
• Menstruation is regulated by the interaction of hormones such as FSH, LH, estrogen, and progesterone.
• These hormones regulate the growth of the uterine lining, ovulation, and shedding of the endometrium if pregnancy does not occur.
• The hypothalamus and pituitary gland also play key roles.
C. The incidence of capability fragility
This phrase is not commonly used medically, but it may refer to the fragility or vulnerability of reproductive capability, such as:
• Reduced fertility or difficulty conceiving
• Decreased ovarian reserve
• Hormonal imbalance
In general, it means how fragile or vulnerable reproductive ability may be.
D. Sustaining the thick endometrium of the uterus
This refers to maintaining the thickened uterine inner lining (endometrium) after ovulation.
• The hormone progesterone, produced by the corpus luteum, keeps the endometrium thick and vascular.
• This prepares the uterus for implantation of a fertilized egg.
• If pregnancy does not occur, progesterone levels drop and menstruation begins.
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Writer: Vandita Singh, Lucknow (GS India Nursing Group)