A. 17-OH progesterone
B. Luteinizing Hormone (LH)
C. Follicle Stimulating Hormone (FSH)
D. Thyroid Stimulating Hormone (TSH)
Correct Answer: B. Luteinizing Hormone (LH)
Explanation
In Polycystic Ovarian Syndrome (PCOS), the hormone that is typically increased is:
✔ Luteinizing Hormone (LH)
- Women with PCOS usually show an elevated LH level, often with an increased LH:FSH ratio (commonly >2:1).
Also Increased in PCOS:
- Androgens (male hormones such as testosterone, androstenedione, DHEAS) are also elevated.
Summary:
Increased in PCOS → LH and Androgens
If you have options, share them and I’ll confirm the correct one.
Other Options Details
Here is a clear and concise description of all the options:
A. 17-OH Progesterone
- 17-Hydroxyprogesterone is a hormone produced in the adrenal glands and ovaries.
- It is an intermediate in the synthesis of cortisol and androgens.
- Clinically, it is commonly measured to diagnose Congenital Adrenal Hyperplasia (CAH) due to 21-hydroxylase deficiency.
- High levels may indicate adrenal hyperplasia, adrenal tumors, or PCOS in some cases.
B. Luteinizing Hormone (LH)
- A hormone released by the anterior pituitary gland.
- In females:
- LH surge triggers ovulation.
- Helps in maintaining corpus luteum.
- In males:
- Stimulates Leydig cells to produce testosterone.
- Measured in infertility evaluation and PCOS (where LH may be elevated).
C. Follicle Stimulating Hormone (FSH)
- Also secreted by the anterior pituitary gland.
- In females:
- Stimulates growth and maturation of ovarian follicles.
- Important in estrogen production.
- In males:
- Stimulates spermatogenesis by acting on Sertoli cells.
- Important in assessing menopause, ovarian reserve, and infertility.
D. Thyroid Stimulating Hormone (TSH)
- Produced by the anterior pituitary gland.
- Regulates the thyroid gland to produce T3 (triiodothyronine) and T4 (thyroxine).
- Elevated TSH = hypothyroidism; Low TSH = hyperthyroidism.
- Thyroid function is important because dysfunction can affect menstrual cycles, fertility, pregnancy, and overall metabolism.
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Writer: Vandita Singh, Lucknow (GS India Nursing Group